14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2044L | α-CGRP (human) acetate | α-CGRP (human) acetate (90954-53-3 free base) | Others |
α-CGRP (human) acetate is a regulatory neuropeptide of 37 amino acids. It is the most potent vasodilator known to date and has inotropic and chronotropic effects. | |||
TP2044 | α-CGRP(human) | α-CGRP (human) | |
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist. | |||
TP1134 | HCGRP-(8-37) | Human α-CGRP (8-37) | |
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist | |||
T36555 | Tyr-α-CGRP (human) (trifluoroacetate salt) | ||
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respecti... | |||
TP1134L | HCGRP-(8-37) acetate | HCGRP-(8-37) acetate (119911-68-1 free base) | CGRP Receptor |
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor. | |||
T76874 | Erenumab | AMG-334 | CGRP Receptor |
Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks. | |||
TP1130 | β-CGRP, human | CGRP-II (Human),Human β-CGRP | |
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at th... | |||
T75978 | β-CGRP, human TFA | ||
Human β-CGRP TFA (β-CGRP, human TFA) is a calcitonin peptide that functions through interaction with the calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP) complex, demonstrating IC50... | |||
T6590 | MK-3207 Hydrochloride | MK-3207 HCl | CGRP Receptor |
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2. | |||
T75788 | α-CGRP(human) TFA | ||
α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as a potent vasodilator [1]. | |||
T12293 | Olcegepant hydrochloride | BIBN-4096 hydrochloride,BIBN4096BS hydrochloride | Others |
Olcegepant hydrochloride is a potent and selective non-peptidethe calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (with IC50 of 0.03 nM for human CGRP). | |||
T76473 | Adrenotensin (human) | ||
Adrenotensin (human) (Pro-ADM-153-185 (human)), a 153-185 fragment of the Adrenomedullin precursor peptide, is part of the Multifunctional Adrenomedullin (ADM). This 52-amino acid peptide, a member of the CGRP superfamil... | |||
T21558 | MK-3207 | ||
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep... | |||
T76678 | Eptinezumab | ||
Eptinezumab, a human monoclonal antibody, specifically binds to and blocks the calcitonin gene-related peptide (CGRP) from binding to its receptor, thus acting as a preventive treatment for migraine in adults [1]. |